Taken during pregnancy, certain antidepressants may increase birth defects, but the risk is quite small. Researchers showed that when used in the first trimester, the SSRI class of antidepressants, which includes Celexa, Paxil, Prozac and Zoloft, was linked to particular defects, including heart and intestinal malformations. But even With the increased risk, the overall chance of having an affected child was still less than 1 percent, which should reassure women who must take the meds during pregnancy.






